LDLR Protein plays a pivotal role in cholesterol homeostasis, binding to LDL and mediating cellular uptake through endocytosis. Clustering into clathrin-coated pits is essential for internalization. In microbial infection, LDLR acts as a receptor for hepatitis C virus in hepatocytes, emphasizing its dual functionality in cholesterol metabolism and the cellular response to viral infections. LDLR Protein, Human (HEK293, His) is the recombinant human-derived LDLR protein, expressed by HEK293 , with C-6*His labeled tag.
Molecular Weight:
Approximately 99-140 kDa due to the glycosylation.
Purity:
95.00
Formula:
3949(Gene_ID)P01130-1 (A22-R788)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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