The NLRP3 protein acts as a sensor in the NLRP3 inflammasome, which is activated in response to membrane defects. It forms a complex with CASP1 and PYCARD/ASC, promotes the release of IL1B, IL18 and GSDMD, and induces pyroptosis. NLRP3 Protein, Human (536a.a, His) is the recombinant human-derived NLRP3 protein, expressed by E. coli , with N-6*His labeled tag.
Molecular Weight:
Approximately 66 kDa, based on SDS-PAGE under reducing conditions.
Purity:
91.00
Formula:
114548(Gene_ID)Q96P20-1 (M1-L536)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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