IL-4R alpha/CD124, Human (HEK293, mFc)

Product Overview

• Article Name: IL-4R alpha/CD124, Human (HEK293, mFc)
• Biozol Catalog Number: MCE-HY-P70325
• Supplier Catalog Number: HY-P70325
• Alternative Catalog Number: MCE-HY-P70325-500UG,MCE-HY-P70325-1MG,MCE-HY-P70325-2UG,MCE-HY-P70325-10UG,MCE-HY-P70325-50UG,MCE-HY-P70325-100UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: IL-4R alpha/CD124 Protein, Human (HEK293, mFc),Human,HEK293

Product Description

IL-4R alpha is a subunit alpha shared by IL-4 and IL-13 receptors, found in leukocytes originally. IL-4R alpha couples to the JAK1/2/3-STAT6 pathway and involves in promoting Th2 differentiation[1]. IL-4R alpha/CD124, Human consists of 825 amino acids (M1-S825) with a transmembrane domain (233-256 a.a) and a soluble form (1-227 a.a). Soluble IL-4R (sIL-4R) inhibits IL4-mediated cell proliferation and IL-5 up-regulation by T-cells[1]. IL-4R alpha/CD124, Human (M26-Q231) is produced in HEK293 cells with a C-Terminal mFc-tag.

Product Properties

• Molecular Weight: Approximately 65-90 kDa due to the glycosylation.
• Purity: 98
• Formula: 3566(Gene_ID)P24394-1 (M26-Q231)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins