Flap endonuclease 1 (FEN-1) is a structure-specific nuclease crucial for DNA replication and repair. In replication, it cleaves 5-overhanging flaps, guiding DNA polymerase and creating a nick for ligation. FEN-1 is integral to the long patch base excision repair pathway, preventing genomic instability. It exhibits 5-3 exonuclease and RNase H activities, playing roles in rDNA and mitochondrial DNA replication and repair. Flap endonuclease 1/FEN-1 Protein, Human is the recombinant human-derived Flap endonuclease 1/FEN-1 protein, expressed by E. coli , with tag free.
Molecular Weight:
Approximately 44.5 kDa
Purity:
95.00
Formula:
2237(Gene_ID)P39748-1 (M1-K380)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
* VAT and and shipping costs not included. Errors and price changes excepted
