GFRA1/GDNFR-alpha-1, Human (HEK293, His)

Product Overview

• Article Name: GFRA1/GDNFR-alpha-1, Human (HEK293, His)
• Biozol Catalog Number: MCE-HY-P70384
• Supplier Catalog Number: HY-P70384
• Alternative Catalog Number: MCE-HY-P70384-10UG,MCE-HY-P70384-50UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: GFRA1/GDNFR-alpha-1 Protein, Human (HEK293, His),Human,HEK293

Product Description

The GFRA1/GDNFR-alpha-1 Protein serves as a receptor for GDNF, facilitating GDNF-induced autophosphorylation and activation of the RET receptor. In a complex, two molecules of GDNFR-alpha-1 are believed to associate with the disulfide-linked GDNF dimer and two molecules of RET. It interacts with RET and SORL1, either alone or in a complex with GDNF, leading to GFRA1 internalization without degradation. GFRA1/GDNFR-alpha-1 Protein, Human (HEK293, His) is the recombinant human-derived GFRA1/GDNFR-alpha-1 protein, expressed by HEK293 , with C-6*His labeled tag.

Product Properties

• Molecular Weight: Approximately 60.0 kDa
• Purity: 98
• Formula: 2674(Gene_ID)P56159-2 (D25-K429)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins