The GDF-15 protein regulates food intake, energy balance, and body weight by binding to its receptor GFRAL. This activates GFRAL-expressing neurons in the brainstem, triggering emergency circuits in the central parabrachial nucleus and amygdala during stress. GDF-15 Protein, Mouse (His) is the recombinant mouse-derived GDF-15 protein, expressed by E. coli, with N-His labeled tag.
Molecular Weight:
Approximately 16-17 kDa, based on SDS-PAGE under reducing conditions.
Purity:
90
Formula:
23886(Gene_ID)Q9Z0J7-1 (S189-A303)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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