MUSK protein is a receptor tyrosine kinase that plays a critical role in the formation of the neuromuscular junction (NMJ). MUSK is activated by the AGRIN-LRP4 complex and regulates the NMJ through gene expression, actin cytoskeleton reorganization, and acetylcholine receptor (AChR) clustering. MUSK Protein, Mouse (HEK293, His) is the recombinant mouse-derived MUSK protein, expressed by HEK293, with C-His labeled tag.
Molecular Weight:
Approximately 60-70 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
18198(Gene_ID)Q61006-1 (E22-T494)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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