SLC40A1 plays a pivotal role in systemic iron homeostasis by transporting Fe(2+) from cells to the bloodstream. Essential for maintaining iron balance, it enables dietary iron uptake, recycling by macrophages and erythrocytes, and controlled release from hepatocytes. In iron surplus, elevated HAMP/hepcidin levels prompt SLC40A1 degradation, limiting iron efflux into the plasma. SLC40A1 Protein, Human (HEK293) is the recombinant human-derived SLC40A1 protein, expressed by HEK293, with tag free.
Molecular Weight:
Approximately 55 kDa, based on SDS-PAGE under reducing conditions.
Purity:
97
Formula:
30061(Gene_ID)Q9NP59 (M1-V571)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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