YAP1 is a multifunctional transcriptional regulator and an important downstream target in the Hippo signaling pathway, affecting organ size control and tumor suppression through proliferation and apoptosis regulation. STK3/MST2 and STK4/MST1 phosphorylate together with SAV1, inactivating YAP1 and WWTR1/TAZ oncoproteins. YAP1 Protein, Human (His) is the recombinant human-derived YAP1 protein, expressed by E. coli, with C-10*His labeled tag.
Molecular Weight:
Approximately 90 kDa, based on SDS-PAGE under reducing conditions.
Purity:
95
Formula:
10413(Gene_ID)P46937 (M1-L504)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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