The LAIR1 protein functions as an inhibitory receptor that negatively regulates NK cells, B cells, and T cells. LAIR1 is activated by tyrosine phosphorylation, recruits PTPN6 and PTPN11, and exerts downstream inhibitory effects. LAIR1 Protein, Mouse (HEK293, mFc) is the recombinant mouse-derived LAIR1 protein, expressed by HEK293, with C-mFc labeled tag.
Molecular Weight:
Approximately 50-66 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
52855(Gene_ID)Q8BG84-1 (Q22-Y141)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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