TNF alpha/TNFSF2, Human (His)

Product Overview

• Article Name: TNF alpha/TNFSF2, Human (His)
• Biozol Catalog Number: MCE-HY-P70426A
• Supplier Catalog Number: HY-P70426A
• Alternative Catalog Number: MCE-HY-P70426A-1MG,MCE-HY-P70426A-500UG,MCE-HY-P70426A-2UG,MCE-HY-P70426A-100UG,MCE-HY-P70426A-50UG,MCE-HY-P70426A-10UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: TNF alpha/TNFSF2 protein, Human (His),Human,E. coli

Product Description

Tumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine[1]. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death[2]. TNF alpha stimulates NF-kappaB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-alpha MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse[3]. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury[4]. TNF alpha/TNFSF2 protein, Human (His) is a recombinant protein with a C-Terminal His label, It consists of 157 amino acids (V77-L233) and is produced in CHO cells.

Product Properties

• Molecular Weight: Approximately 18 kDa, based on SDS-PAGE under reducing conditions.
• Purity: 97.00
• Formula: 7124(Gene_ID)P01375 (V77-L233)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins