IL-37 protein is an important immunoregulatory cytokine that suppresses innate inflammation and immune responses and reduces excessive inflammation. It signals intracellularly through nuclear translocation of SMAD3 and extracellularly through binding to its receptors, consisting of IL18R1 and IL18RAP. IL-37 Protein, Human (His) is the recombinant human-derived IL-37 protein, expressed by E. coli, with C-His labeled tag.
Molecular Weight:
Approximately 20-23 kDa,based on SDS-PAGE under reducing conditions.
Formula:
27178(Gene_ID)Q9NZH6-2 (L27-K192)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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