The IL-5 Protein, predominantly expressed by T-lymphocytes and NK cells, is crucial for eosinophil survival, differentiation, and chemotaxis. It also affects B-cells, inducing immunoglobulin production, growth, and differentiation. IL-5 Protein activates kinases like LYN, SYK, and JAK2, which signal through RAS-MAPK and JAK-STAT5 pathways. It exists as a disulfide-linked homodimer and interacts with IL5RA and CSF2RB subunits. IL-5 Protein, Human (HEK293) is the recombinant human-derived IL-5 protein, expressed by HEK293, with tag free.
Molecular Weight:
Approximately 15-21 kDa,based on SDS-PAGE under reducing conditions,36 kDa,based on SDS-PAGE under non-reduced conditions,due to the glycosylation.
Formula:
3567(Gene_ID)P05113-1 (I20-S134)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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