IL-8/CXCL8 protein, a vital chemotactic factor, orchestrates inflammatory responses by attracting neutrophils, basophils, and T-cells to clear pathogens. It activates neutrophils and binds to CXCR1/CXCR2 receptors, initiating downstream signaling pathways. IL-8/CXCL8 homodimerizes, disrupted by tick evasin-3, and interacts with TNFAIP6, potentially regulating chemokine activity in the inflammatory microenvironment. IL-8/CXCL8 Protein, Human (HEK293) is the recombinant human-derived IL-8/CXCL8 protein, expressed by HEK293, with tag free.
Molecular Weight:
Approximately 6-12 kDa,based on SDS-PAGE under reducing conditions,11 kDa,based on SDS-PAGE under non-reduced conditions,due to the glycosylation.
Purity:
95
Formula:
3576(Gene_ID)P10145-1 (S28-S99)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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