FLT3 is a tyrosine-protein kinase receptor that regulates differentiation, proliferation, and survival of hematopoietic progenitor cells and dendritic cells. It phosphorylates downstream effectors such as SHC1 and AKT1, activating signaling cascades involving MTOR, RAS, and MAP kinases. FLT3 Protein, Human (HEK293, His) is the recombinant human-derived FLT3 protein, expressed by HEK293, with C-His labeled tag.
Molecular Weight:
Approximately 70-90 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Formula:
2322(Gene_ID)P36888-1 (N27-S543)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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