SDF-1 alpha (CXCL12alpha) belongs to the CXC chemokine family and is encoded by the CXCL12 gene. SDF-1 alpha mediates cell chemotaxis and tissue repair through CXCR4/CXCR7, activates AMPK to inhibit NLRP3 inflammasome and pyroptosis, SDF-1 alpha promotes autophagy through the PI3K-mTOR pathway, is induced by upstream inflammatory factors such as TNF-alpha, and recruits integrins downstream to promote cell adhesion[1]. SDF-1 alpha/CXCL12 Protein, Human is the recombinant human-derived SDF-1 alpha/CXCL12 protein, expressed by E. coli, with tag free.
Molecular Weight:
Approximately 8 kDa, based on SDS-PAGE under reducing conditions.
Purity:
98
Formula:
6387(Gene_ID)P48061-2 (K22-K89)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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