NOTCH1 protein is a receptor for the ligands JAG1, JAG2 and DLL1 and is critical for cell fate decisions. Upon ligand activation, NICD forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes in the cleavage site enhancer. NOTCH1 Protein, Human (HEK293, His) is the recombinant human-derived NOTCH1 protein, expressed by HEK293, with C-His labeled tag.
Molecular Weight:
Approximately 65 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
90
Formula:
4851(Gene_ID)P46531 (A19-Q526)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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