NOTCH2 protein is a receptor for ligands such as JAG1, JAG2 and DLL1 and is critical for cell fate determination. Ligand activation promotes cleavage and releases NICD, which forms a transcription activator complex with RBPJ/RBPSUH, affecting cell differentiation, proliferation and apoptosis. NOTCH2 Protein, Human (HEK293, Fc) is the recombinant human-derived NOTCH2 protein, expressed by HEK293, with C-hFc labeled tag.
Molecular Weight:
Approximately 90 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Formula:
4853(Gene_ID)Q04721 (L26-Q530)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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