TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-alpha). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI. TNF RII/TNFRSF1B Protein, Mouse (HEK293, His) is expressed by HEK293 and has a transmembrane region with 6*His tag at the C-terminus[1].
Molecular Weight:
Approximately 33-55 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
