Noggin is an antagonist of bone morphogenetic proteins (BMPs) and a member of the TGF-beta superfamily, existing as a homodimer. Noggin binds to BMP-2/-4/-7 and inhibits their binding to BMPR-I/II receptors, thereby synergistically inducing bone differentiation in HMSCs, maintaining pluripotency in hESCs, inhibiting angiogenesis in HUVECs, and promoting myelination in oligodendrocytes, exerting neural activity[1][2][3][4]. Noggin Protein, Human (CHO) is a recombinant human Noggin protein expressed in CHO cells with tag-free.
Molecular Weight:
Approximately 27-36 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
96.80
Formula:
9241(Gene_ID)Q13253 (Q28-C232)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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