PD-1 protein is an inhibitory receptor on T cells that maintains immune tolerance by binding to CD274/PDCD1L1 and CD273/PDCD1LG2. It blocks T cell activation by binding to CD3-TCR and recruiting PTPN11/SHP-2 to dephosphorylate key signaling molecules. PD-1 Protein, Human (HEK293, mFc) is the recombinant human-derived PD-1 protein, expressed by HEK293 , with C-mFc labeled tag.
Molecular Weight:
55-70 kDa
Purity:
98.96
Formula:
5133(Gene_ID)Q15116 (P21-Q167)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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