IL-12 beta Protein, also known as natural killer cell stimulatory factor 2, is a common subunit (p40) of IL-12 and IL-23. IL-12 is a inflammatory factor expressed by activated macrophages, and involves in Th1-type immune response against cancer[1]. IL-12 beta Protein located outside the cell membrane, involves in singalling mediated by Jak-STAT[3]. IL-12 beta Protein consists of 328 amino acids (M1-S328) with a fibronectin type-III domain (237-328 a.a). IL-12 beta Protein, Human (I23-S328) is produced in HEK293 cells with tag free.
Molecular Weight:
Approximately 40-47 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
95.83
Formula:
3593(Gene_ID)P29460 (I23-S328)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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