FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively[1]. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization[2].FGF-2 Protein, Mouse (145a.a), consists of 145 amino acids, produced by E.coli with tag free.
Molecular Weight:
Approximately 17 kDa, based on SDS-PAGE under reducing conditions.
Purity:
97.00
Formula:
14173(Gene_ID)P15655 (P10-S154)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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