IL-36 alpha/IL-1F6, Human

Product Overview

• Article Name: IL-36 alpha/IL-1F6, Human
• Biozol Catalog Number: MCE-HY-P70702
• Supplier Catalog Number: HY-P70702
• Alternative Catalog Number: MCE-HY-P70702-50UG,MCE-HY-P70702-10UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: IL-36 alpha/IL-1F6 Protein, Human,Human,E. coli

Product Description

IL-36 alpha (IL-1F6), a subform of IL-36 family, belongs to IL-1 superfamily. IL-36 alpha mediates inflammatory response. IL-36 alpha binds to IL-36R and activates NF-kappaB and MAPK signaling pathways, but the activation requires N-terminal cleavage by neutrophil granule-derived proteases[1]. IL-36 alpha also binds to IL-1Rrp2 and recruit IL-1RAcP. IL-36 alpha activats the MAPK, Erk1/2 and JNK through IL-36R/IL-1RAcP[2]. IL-36 alpha/IL-1F6 Protein, Human is a recombinant human IL-36 alpha without any tag, which is produced in E. coli.

Product Properties

• Molecular Weight: Approximately 17 kDa, based on SDS-PAGE under reducing conditions.
• Purity: 98
• Formula: 27179(Gene_ID)Q9UHA7 (K6-F158)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins