LAG-3 (lymphocyte activating gene 3) protein is an inhibitory receptor on antigen-activated T cells and is critical for immune regulation. LAG-3 binds to FGL1 and transmits inhibitory signals that negatively affect CD8(+) and CD4(+) T cell proliferation, activation, and effector functions. LAG-3 Protein, Human (HEK293, His) is the recombinant human-derived LAG-3 protein, expressed by HEK293 , with C-6*His labeled tag.
Molecular Weight:
60-80 kDa
Purity:
98
Formula:
3902(Gene_ID)P18627-1 (L23-L450)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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