ROR1 proteins minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo. It serves as a receptor for WNT5A, activating NFkB signaling and potentially inhibiting WNT3A signaling. Notably, ROR1 plays a vital role in the inner ear, facilitating innervation of auditory hair cells by spiral ganglion neurons. ROR1 Protein, Human (HEK293, His) is the recombinant human-derived ROR1 protein, expressed by HEK293 , with C-6*His labeled tag.
Molecular Weight:
Approximately 60-80 kDa, based on SDS-PAGE under reducing conditions.
Purity:
98
Formula:
4919(Gene_ID)Q01973-1 (Q30-E403)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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