SCF proteins are ligands for the KIT receptor-type protein tyrosine kinase and regulate a variety of cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Binding to KIT activates signaling pathways involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinase, STAT family members, and PLCG1, producing diacylglycerol and inositol 1,4,5-trisphosphate. SCF Protein, Human (HEK293, His) is the recombinant human-derived SCF protein, expressed by HEK293 , with C-6*His labeled tag.
Molecular Weight:
Approximately 30-50 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
98
Formula:
4254(Gene_ID)P21583-1 (E26-H214)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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