The LRRC25 protein is an important regulator that inhibits RLR-mediated type I interferon signaling by coordinating the autophagic degradation of RIGI. Its specific interaction with ISG15-related RIGI promotes binding to p62/SQSTM1, leading to selective autophagic RIGI degradation. LRRC25 Protein, Human (HEK293, His) is the recombinant human-derived LRRC25 protein, expressed by HEK293 , with C-6*His labeled tag.
Molecular Weight:
Approximately 20-40 kDa,based on SDS-PAGE under reducing conditions.
Formula:
126364(Gene_ID)Q8N386 (L21-T165)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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