The ERP27 protein has a unique role in that it can specifically bind unfolded proteins and recruit the protein disulfide isomerase PDIA3 to the substrate through the hydrophobic pocket in its C-terminal domain. This interaction implies that ERP27 is involved in the unfolding stress response and resolves challenges in cellular proteostasis. ERP27 Protein, Human (HEK293, His) is the recombinant human-derived ERP27 protein, expressed by HEK293 , with C-6*His labeled tag.
Molecular Weight:
Approximately 32-38 kDa,based on SDS-PAGE under reducing conditions.
Formula:
121506(Gene_ID)Q96DN0 (E26-L273)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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