FZD2 is a Wnt receptor that primarily activates the beta-catenin classical pathway, involving disheveled protein, GSK-3 kinase inhibition, nuclear beta-catenin accumulation, and Wnt target gene activation. Although some family members exhibit second PKC and calcium flux pathways, the precise differentiation and integration with the canonical pathways remains unclear. FZD2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived FZD2 protein, expressed by HEK293 , with C-hFc labeled tag.
Molecular Weight:
Approximately 55-60 kDa,based on SDS-PAGE under reducing conditions.
Formula:
57265(Gene_ID)Q9JIP6 (Q29-L168)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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