As an E3-type SUMO ligase, ZBED1 protein catalyzes CHD3/Mi2-alpha sumoylation, relieves transcriptional repression and promotes the recruitment of RNA polymerase II to gene promoters. This positively regulates H1-5, RPS6, RPL10A and RPL12 transcription, enhancing cell proliferation and growth. ZBED1 Protein, Human (His) is the recombinant human-derived ZBED1 protein, expressed by E. coli , with C-6*His labeled tag.
Molecular Weight:
Approximately 14 kDa, based on SDS-PAGE under reducing conditions.
Purity:
98
Formula:
9189(Gene_ID)O96006 (N3-E100)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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