SHP-1 Protein modulates signaling from tyrosine-phosphorylated cell surface receptors, including KIT and EGFR. It enhances the inhibition of mast cell activation via the Lilrb4a receptor. The SH2 regions interact with cellular components to regulate its phosphatase activity. In collaboration with MTUS1, it induces UBE2V2 expression upon angiotensin II stimulation. SHP-1 plays a crucial role in hematopoiesis. SHP-1 Protein, Human (His) is the recombinant human-derived SHP-1 protein, expressed by E. coli , with C-6*His labeled tag.
Molecular Weight:
Approximately 33.0 kDa
Purity:
98
Formula:
5777(Gene_ID)AAH02523.1 (K243-I541)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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