TREM-2 protein forms a signaling complex with TYROBP, activates cells upon ligand binding, and acts as a receptor for amyloid beta, lipoproteins, and apolipoproteins. It promotes their uptake by microglia, triggering activation, proliferation, migration, apoptosis and cytokine expression. TREM-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived TREM-2 protein, expressed by HEK293 , with C-6*His labeled tag.
Molecular Weight:
Approximately 25-40 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Purity:
98
Formula:
83433(Gene_ID)Q99NH8-1 (L19-P168)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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