The TRIM5 protein is a capsid-specific restriction factor that prevents non-host adapted retroviral infection. TRIM5 acts as a pattern recognition receptor that activates innate immune signaling by triggering E3 ubiquitin ligase activity upon binding to viral capsids. TRIM5 restricts various retroviruses and regulates autophagy. TRIM5 Protein, Human (N-His) is the recombinant human-derived TRIM5 protein, expressed by E. coli , with N-6*His labeled tag.
Molecular Weight:
Approximately 30 kDa, based on SDS-PAGE under reducing conditions.
Purity:
95
Formula:
85363(Gene_ID)Q9C035-1 (M1-Q248)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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