UBE2M Protein is a crucial mediator in the ubiquitin-like protein NEDD8 conjugation pathway. It accepts NEDD8 from the UBA3-NAE1 E1 complex, covalently attaching it to target proteins like CUL1, CUL2, CUL3, and CUL4, particularly interacting with the E3 ubiquitin ligase RBX1. This specificity in neddylating specific targets suggests a pivotal role in regulating cellular processes, notably contributing to cell proliferation. UBE2M Protein, Human is the recombinant human-derived UBE2M protein, expressed by E. coli , with tag free.
Molecular Weight:
Approximately 20 kDa, based on SDS-PAGE under reducing conditions.
Purity:
98
Formula:
9040(Gene_ID)P61081 (M1-K183)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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