The UBE2V1 protein does not have intrinsic ubiquitin ligase activity and can cooperate with UBE2N to synthesize non-canonical polyubiquitin chains linked through Lys-63. This type of polyubiquitination activates IKK and mediates NF-kappa-B activation, thereby affecting transcriptional activation, cell cycle progression, and DNA repair. UBE2V1 Protein, Human (His) is the recombinant human-derived UBE2V1 protein, expressed by E. coli , with C-6*His labeled tag.
Molecular Weight:
Approximately 17 kDa, based on SDS-PAGE under reducing conditions.
Formula:
7335(Gene_ID)Q13404 (A2-N147)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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