The GFRAL protein is a brainstem-restricted receptor for GDF15 that regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stress. GFRAL binds to its ligand GDF15, interacts with RET, and activates the MAPK and AKT signaling pathways. GFRAL Protein, Human (His-SUMO) is the recombinant human-derived GFRAL protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
Molecular Weight:
Approximately 53.8 kDa
Purity:
93.00
Formula:
389400(Gene_ID)Q6UXV0 (S19-E351)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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