SAE1 protein, forming a heterodimer, acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and potentially SUMO4. It critically mediates ATP-dependent activation of SUMO proteins, enabling the formation of a thioester bond with UBA2/SAE2s active site cysteine. This process is essential for protein modification through sumoylation. SAE1 Protein, Human (GST) is the recombinant human-derived SAE1 protein, expressed by E. coli , with N-GST labeled tag.
Molecular Weight:
Approximately 65.4 kDa
Formula:
10055(Gene_ID)Q9UBE0 (M1-K346)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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