IL-1 alpha, a cytokine present in non-hematopoietic cells, links innate and adaptive immunity. Binding to its receptor IL1R1, IL-1 alpha forms a receptor complex, activating signaling pathways involving MYD88, IRAK1, and IRAK4. It activates NF-kappa-B and MAPK pathways. Released during cell death, IL-1 alpha induces inflammation, senses DNA damage, and interacts with TMED10, IL1R1, and S100A13 for secretion and plasma membrane translocation. IL-1 alpha Protein, Rhesus macaque is the recombinant Rhesus Macaque-derived IL-1 alpha protein, expressed by E. coli , with tag free.
Molecular Weight:
Approximately 18-20 kDa, based on SDS-PAGE under reducing conditions.
Purity:
97.00
Formula:
700193(Gene_ID)P48089 (S113-A271)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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