CD46 Protein serves as a cofactor for complement factor I, safeguarding cells against complement-induced harm. It aids in sperm-oocyte fusion and acts as a T-cell costimulatory factor, facilitating the formation of T-regulatory 1 cells. These cells secrete interleukin-10, suppressing immune responses and preventing autoimmunity. Pathogens can exploit CD46s immune regulation abilities to induce an immunosuppressive state in T-cells. CD46 Protein, Human (HEK293, hFc) is the recombinant human-derived CD46 protein, expressed by HEK293 , with C-hFc labeled tag.
Molecular Weight:
Approximately 70.0 kDa
Purity:
95.00
Formula:
4179(Gene_ID)P15529-1 (C35-Y328)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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