CD40L/CD154/TRAP, Human (HEK293, hFc-Flag)

Product Overview

• Article Name: CD40L/CD154/TRAP, Human (HEK293, hFc-Flag)
• Biozol Catalog Number: MCE-HY-P72028
• Supplier Catalog Number: HY-P72028
• Alternative Catalog Number: MCE-HY-P72028-2UG,MCE-HY-P72028-100UG,MCE-HY-P72028-10UG,MCE-HY-P72028-500UG,MCE-HY-P72028-5UG,MCE-HY-P72028-50UG,MCE-HY-P72028-1MG,MCE-HY-P72028-250UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: CD40L/CD154/TRAP Protein, Human (HEK293, hFc-Flag),Human,HEK293

Product Description

CD40L (CD154, TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis[1]. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-kappaB/MAPK pathway[2][3]. CD40L also involves in B cell differentiation, maturation, and apoptosis[4]. CD40L in human, cleaved into 2 chains of membrane form (1-261 a.a.) and soluble form (113-261 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). CD40L/CD154/TRAP Protein, Human (HEK293, hFc-Flag) has a total length of 248 amino acids (M13-L261), is expressed in HEK392 cells with N-terminal hFc- and Flag-tag.

Product Properties

• Molecular Weight: Approximately 44-50 kDa due to the glycosylation.
• Purity: 97.00
• Formula: 959(Gene_ID)P29965 (M113-L261)(Accession)

Application Notes

• Application Notes: Recombinant Proteins