Reelin/RELN, Human (P.pastoris, His)

Product Overview

• Article Name: Reelin/RELN, Human (P.pastoris, His)
• Biozol Catalog Number: MCE-HY-P72276
• Supplier Catalog Number: HY-P72276
• Alternative Catalog Number: MCE-HY-P72276-50UG,MCE-HY-P72276-20UG,MCE-HY-P72276-10UG,MCE-HY-P72276-100UG,MCE-HY-P72276-2UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: Reelin/RELN Protein, Human (P.pastoris, His),Human,P. pastoris

Product Description

Reelin/RELN is a secretory glycoprotein belonging to the extracellular matrix family. Reelin/RELN can bind to ApoER2/VLDLR to activate Src family kinase-mediated Dab1 phosphorylation, initiate PI3K/Akt/mTOR signaling to regulate neuronal migration and synaptic plasticity. Reelin/RELN also activates Rap1 to regulate the actin skeleton, and terminates Reelin/RELN signaling through Cul5/Rbx2/SOCS7 and ADAMTS-4/5. Reelin/RELN abnormalities are closely related to diseases such as lissencephaly caused by RELN mutations, autism, schizophrenia, and Alzheimers disease. Reelin/RELN Protein, Human (P. pastoris, His) is a recombinant human Reelin/RELN protein expressed from P. pastoris with an N-6*His tag.

Product Properties

• Molecular Weight: 26-30 kDa
• Purity: 98
• Formula: 5649(Gene_ID)P78509 (A26-T254)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins