Bone morphogenetic protein 15 (BMP-15, GDF9B), also known as growth differentiation factor 9B (GDF9B), is a polymorphic ligand protein of the TGFbeta family and is only expressed in follicular cells. BMP15 is closely related to GDF9 and synergistically regulates the genetic development of follicles. BMP15 is involved in p38 MAPK and HIF-1alpha/SCF signaling pathway, respectively, and can up-regulate the expression of anti-Mullerian hormone (AMH) and polycystic ovarian syndrome (PCOS) related stem cell factor (SCF) in granulosa cells.
Molecular Weight:
Approximately 23 kDa, based on SDS-PAGE under reducing conditions.
Purity:
97.00
Formula:
9210(Gene_ID)O95972 (Q268-R392)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
* VAT and and shipping costs not included. Errors and price changes excepted
