IFN-gamma R1/CD119 Protein, Human (HEK293, His, solution),Human,HEK293
IFN-gamma R1 (CD119), one of the subunit of IFN-gamma receptor, is a receptor for IFN-gamma. IFN-gamma R1 forms the functional receptor with IFN-gamma R2. Upon binding with IFN-gamma,IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate[1]. Then, JAK1 and JAK2 are phosphorylated and activated, and STAT1 is recruited to the receptor complex. Phosphorylated STAT1 translocates to the nucleus, where it regulates the expression of IFN-responsive genes (e.g. CD54)[2]. IFN-gamma R1/CD119 Protein, Human (HEK293, His, solution) is a recombinant human IFN-gamma R1 (E18-G245) with C-terminal 6*His tag, which is produced in HEK293 cells.
Molecular Weight:
40-50 kDa
Purity:
95
Formula:
3459(Gene_ID)P15260-1 (E18-G245)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
* VAT and and shipping costs not included. Errors and price changes excepted
