Nerve Growth Factor Receptor (NGFR) also known as CD271, p75NTR, TNFRSF16, is a transmembrane low-affinity receptor for the neurotrophin family. NGFR has no intrinsic tyrosine kinase activity. NGFR can act as a tumour suppressor, negatively regulating cell growth and proliferation[1]. NGF-NGFR cascade activates NF-kappaB, leading to inhibition of apoptosis, increases survival of schwannoma, and breast cancer cells[3]. NGFR Protein, Human (HEK293) is a recombinant protein consisting of 222 amino acids (K29-N250) and is produced in HEK293 cells.
Molecular Weight:
Approximately 42-58 kDa due to the glycosylation.
Purity:
95.00
Formula:
4804(Gene_ID)P08138-1 (K29-N250)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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