CD70 is the ligand of CD27 in activated T and B lymphocytes, is an important cytokine in CD70-CD27 pathway involving with the generation and maintenance of T cell immunity[1]. CD70 is a surface antigen, also shows antiviral activity and regulates viability of tumor cells and regulatory T cells[2][3]. As for CD70 protein in mouse contains TNF_2 domain and transmembrane helix, belonging to the tumor necrosis factor (TNF) family. CD70 Protein, Mouse (HEK293, Fc) is expressed in the HEK293 cells with N terminal 10*His-tag.
Molecular Weight:
Approximately 25-30 kDa,based on SDS-PAGE under reducing conditions.
Formula:
21948(Gene_ID)Q05A52 (Q47-P195)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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