CD161 protein plays a crucial role in inhibiting NK cell toxicity by activating specific acid sphingomyelinase/SMPD1 and increasing ceramide levels. Activation stimulates AKT1/PKB and RPS6KA1/RSK1 kinases, enhancing anti-CD3-induced T cell proliferation. CD161 Protein, Human (HEK293, Fc) is the recombinant human-derived CD161 protein, expressed by HEK293 , with C-hFc labeled tag.
Molecular Weight:
55-70 kDa
Purity:
98
Formula:
3820(Gene_ID)Q12918 (Q67-S225)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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