CDKN2A Protein, a potent negative regulator of cell proliferation, forms strong interactions with CDK4 and CDK6, hindering their association with cyclins D and retinoblastoma protein phosphorylation. Acting in a heterodimeric manner, predominantly with CDK6, CDKN2A inhibits cyclin D-CDK4 kinase activity and interacts with ISCO2, contributing to its cell cycle regulatory role. CDKN2A Protein, Human is the recombinant human-derived CDKN2A protein, expressed by E. coli , with tag free.
Molecular Weight:
Approximately 19.12 kDa
Purity:
99.00
Formula:
1029(Gene_ID)P42771 (E2-D156)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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