MME Protein, with thermolysin-like specificity, crucially degrades opioid peptides like Met- and Leu-enkephalins, cleaving a Gly-Phe bond.It also catalyzes the cleavage of bradykinin, substance P, neurotensin peptides, angiotensin-1, angiotensin-2, and angiotensin 1-9.Involved in atrial natriuretic factor (ANF) degradation, MME exhibits UV-inducible elastase activity towards skin preelastic and elastic fibers.MME Protein, Mouse (HEK293, His) is the recombinant mouse-derived MME protein, expressed by HEK293 , with N-His labeled tag.