IL-3, secreted by T-lymphocytes, mast cells, and osteoblastic cells, controls hematopoietic cell production and differentiation.It stimulates basophils, eosinophils, and monocytes, and promotes neural cell proliferation.IL-3 inhibits osteoclast differentiation and activates JAK2-STAT5 pathway.In non-hematopoietic systems, it activates PI3K/AKT and ERK pathways for cell survival under oxidative stress.IL-3 Protein, Rat (sf9, His) is the recombinant rat-derived IL-3 protein, expressed by Sf9 insect cells , with C-6*His labeled tag.
Molecular Weight:
Approximately 24 kDa, based on SDS-PAGE under reducing conditions.
Purity:
95
Formula:
24495(Gene_ID)P97688 (I27-C169)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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